Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Good
Based on 7 Reviews
8.6
Supplement Facts
Serving Size:   1 Capsule
Amount Per Serving
%DV
Oregano (leaf and flower) Oil containing 75% carvacrol (37.5 mg)
50 mg
**
Flaxseed Oil
25 mg
**

Top Medical Research Studies

We explored the antimicrobial potential of oregano essential oil (O. vulgare) against pathogens linked to vaginal infections. Using microdilution methods, we determined the minimum inhibitory concentration (MIC) and the minimum bactericidal/fungicidal concentration (MBC/MFC) of various clinical strains from women experiencing symptoms.

Our findings showed that certain strains, particularly Escherichia coli and Candida albicans, were especially susceptible to oregano oil. Notably, we observed that the oil inhibited the growth of C. albicans, limiting its filamentation at a concentration of just 0.45 μl/ml. This suggests oregano could play a significant role in addressing yeast infections.

The efficiency of oregano essential oil in combating these infections is promising, as we found quicker determination of its effectiveness within just 24 hours. Overall, this study opens doors for considering oregano oil as a complementary treatment option in gynecological practice, especially for yeast infections.
Read More
We evaluated the antifungal effects of oregano essential oils on yeast infections in this study. The essential oils from oregano and another source were analyzed using advanced laboratory techniques to understand their composition and active ingredients.

We looked at how effective these essential oils, particularly the main component carvacrol, were against 27 clinical isolates of yeast. By applying standardized lab protocols, we were able to determine the minimum amount needed to inhibit growth, known as minimum inhibitory concentrations (MICs). The results were promising, with MIC values ranging from 450 to 900 μg/ml.

Interestingly, the antifungal properties of the essential oils showed no difference across both sensitive and resistant fluconazole isolates, indicating a consistent efficacy. Our findings suggest that oregano essential oils and carvacrol could be potential agents in combating yeast infections associated with human health issues.
Read More
8
Oregano oil shows promising antifungal effects
We investigated how oregano essential oil affects Candida albicans, a common cause of yeast infections. In our study, we looked at 30 different vaginal strains of this yeast isolated from patients. We were particularly interested in comparing the effectiveness of oregano to established antifungal treatments like clotrimazole, fluconazole, and itraconazole.

Using methods like the agar disc diffusion and microdilution techniques, we discovered that oregano essential oil, alongside other oils like mint and tea tree oil, showed a remarkable ability to inhibit the growth of C. albicans. In fact, the essential oils often worked even better than clotrimazole.

We also explored how these oils caused damage to the yeast cells, finding that they specifically affected the cell wall and membranes. This cellular damage was more pronounced than what we observed with traditional medications.

Overall, our findings suggest that oregano essential oil holds promise as a powerful alternative or supplementary treatment for managing yeast infections.
Read More

Most Useful Reviews

9
Battled yeast infections
82 people found this helpful
Effective! This is my second order of oregano supplements. As someone with type 2 diabetes and an alcohol problem, I constantly battled yeast infections. In three weeks, I noticed no signs or symptoms of yeast infections, and the itchy back issue I had was resolved. I would highly recommend it.
Read More
7.5
Helpful daily supplement
10 people found this helpful
A must-have for me as a daily supplement due to my ongoing issues with yeast infections. Taking 2 a day at the same time has been extremely beneficial, while taking them separately yielded no noticeable difference.
Read More
9
Cleared itching quickly
5 people found this helpful
Amazing product that everyone needs. I started taking 2 a day with 2 garlic pills and 2 aloe vera pills along with a Milk Thistle pill, and I got rid of Candida, which had me itching all over and suffering from a terrible yeast infection. After 4 days on this regime, I experienced an unexpected diarrhoea, but the itching eventually subsided. I continue with the regime, now taking 1 pill a day instead of 2. Thank God for this Oregano Oil.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
  • All Researches
We investigated the potential of oregano essential oil (OEO) encapsulated in keratin microparticles as an alternative treatment for vulvovaginal candidiasis (VVC), a common fungal infection among women. The main goal was to develop a method that would protect the essential oil and control its release, making it more effective against the fungal infection.

Our results showed that the oregano-loaded microparticles were stable over time and had a high encapsulation efficiency. We found that these microparticles not only penetrated well but also completely stopped the growth of the Candida yeast in a laboratory setting. Impressively, when we tested the microparticles in mice infected with Candida, a single application significantly reduced the yeast count while preserving beneficial bacteria.

This innovative approach using oregano essential oil microparticles presents a promising and natural alternative or complementary solution for treating yeast infections like VVC, while also maintaining the balance of healthy vaginal flora.
Read More
9
Oregano oil impacts yeast virulence
We examined how Origanum vulgare essential oil (commonly known as oregano oil) and its active compound, carvacrol, affect the virulence factors of yeast species, particularly Malassezia sympodialis and Malassezia furfur. These fungi, while part of our skin's natural microbiota, can also lead to stubborn skin infections that are difficult to treat with conventional antifungals.

Our findings revealed that both oregano oil and carvacrol have antifungal properties that make them effective against these yeast species. More importantly, we noted that carvacrol demonstrated greater activity and lower toxicity at low concentrations compared to oregano oil.

Notably, we observed that in the presence of either oregano oil or carvacrol, Malassezia sympodialis showed a marked reduction in its ability to adhere to surfaces and form biofilms. Additionally, both yeast species displayed decreased hydrophobicity when exposed to carvacrol. These effects suggest that oregano and its compounds could help manage yeast infections more effectively, especially in the face of rising drug resistance.

However, we recognize that further investigations are needed to fully understand the mechanisms behind these inhibitory effects and how they might be utilized in clinical settings.
Read More
We examined the antifungal properties of oregano essential oil as a potential treatment for yeast infections. Our study involved testing 44 strains from six different fungal species, employing methods like determining minimal inhibitory concentrations (MICs), inhibiting biofilm formation, and evaluating toxicity.

Our findings indicate that oregano essential oil demonstrated strong antifungal activity, with MIC values below 3.125 mg/mL, making it one of the most effective choices amongst the oils tested. Additionally, in our antibiofilm studies, oregano significantly reduced biofilm formation, showing its potential for managing fungal infections.

In juxtaposition to other essential oils like lavender and thyme, which also exhibited notable antifungal properties, oregano stood out for its effectiveness. However, further research is necessary to fully understand the safety and efficacy of oregano oil as a topical treatment for candidiasis, which remains a widespread issue.

We believe these insights could benefit those seeking alternative treatments for yeast infections, with oregano essential oil being a promising candidate.
Read More
We investigated how essential oils from three Algerian oregano species—Origanum glandulosum, Ammoides verticillata, and Saccocalyx satureioides—can affect yeast infections caused by two Candida species, Candida albicans and Candida glabrata. By testing these oils against both individual strains and mixed biofilms, we aimed to assess their potential as natural antifungal treatments.

Using a variety of methods, including disc diffusion and broth microdilution, we evaluated how effective the essential oils were against these yeast cells. We discovered that the oils were not only able to inhibit the growth of the yeast at certain concentrations but also to deal with biofilms, which are notoriously difficult to treat. Interestingly, we found that at concentrations of 500 to 1000 µg/mL, the oils could disrupt and even destroy the biofilms.

Scanning electron microscopy confirmed that Origanum glandulosum caused significant damage to these biofilms, revealing its promising potential in treating these stubborn infections. Additionally, when we combined Origanum glandulosum with amphotericin B, a standard antifungal, the effect was even more pronounced against Candida albicans.

Overall, our findings indicate that these Algerian essential oils show significant antifungal and antibiofilm activities, suggesting that they could be valuable candidates for managing oral Candida infections effectively.
Read More
We set out to investigate how Origanum vulgare L. essential oil, commonly known as oregano oil, affects yeast infections caused by Candida species. Specifically, we aimed to determine whether this natural remedy could inhibit various virulence factors associated with these infections and enhance the effects of traditional antifungal medications like fluconazole and nystatin.

During our research, we analyzed both clinical strains of Candida albicans and several non-albicans strains. We employed various tests to measure oregano oil's influence on yeast growth, adherence to surfaces, and biofilm formation, which are all critical factors in the virulence of these fungi.

Our findings showed that oregano oil significantly reduced the growth and harmful behaviors of the Candida strains we tested. We identified minimum inhibitory concentrations indicating that small amounts of oregano oil could effectively inhibit yeast growth. Additionally, oregano oil demonstrated a synergistic effect when combined with fluconazole and nystatin, meaning it helped these medications work even better against the yeast.

Overall, oregano oil could be a valuable addition to antifungal treatments, offering a promising approach to combatting recurring yeast infections. This research highlights its potential as a natural remedy that, when paired with conventional therapies, could enhance treatment outcomes.
Read More

User Reviews

USERS' SCORE
Good
Based on 7 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Battled yeast infections
82 people found this helpful
Effective! This is my second order of oregano supplements. As someone with type 2 diabetes and an alcohol problem, I constantly battled yeast infections. In three weeks, I noticed no signs or symptoms of yeast infections, and the itchy back issue I had was resolved. I would highly recommend it.
Read More
7.5
Helpful daily supplement
10 people found this helpful
A must-have for me as a daily supplement due to my ongoing issues with yeast infections. Taking 2 a day at the same time has been extremely beneficial, while taking them separately yielded no noticeable difference.
Read More
9
Cleared itching quickly
5 people found this helpful
Amazing product that everyone needs. I started taking 2 a day with 2 garlic pills and 2 aloe vera pills along with a Milk Thistle pill, and I got rid of Candida, which had me itching all over and suffering from a terrible yeast infection. After 4 days on this regime, I experienced an unexpected diarrhoea, but the itching eventually subsided. I continue with the regime, now taking 1 pill a day instead of 2. Thank God for this Oregano Oil.
Read More
9
Effective yeast treatment
Excellent for any intestinal infection, this quality product works well. It aids in addressing yeast infections and other uncomfortable situations.
Read More
9
Prevents yeast infections
This oregano oil is essential in my home. At the first hint of a sore throat or any infection, I use it, and it prevents further issues.
Read More

Frequently Asked Questions

9
Effective yeast treatment
Excellent for any intestinal infection, this quality product works well. It aids in addressing yeast infections and other uncomfortable situations.
9
Prevents yeast infections
This oregano oil is essential in my home. At the first hint of a sore throat or any infection, I use it, and it prevents further issues.
7.5
Fights yeast infections
This oil effectively combats bacteria, fungi, and yeast infections. It aids in expelling parasites, combats respiratory viruses, and alleviates skin issues.
7.5
Strong yeast fighter
This herbal oil acts as a robust antimicrobial agent, effective in fighting infections, including yeast infections, as prescribed by my doctor for gastrointestinal issues.
We examined the antifungal properties of oregano essential oil as a potential treatment for yeast infections. Our study involved testing 44 strains from six different fungal species, employing methods like determining minimal inhibitory concentrations (MICs), inhibiting biofilm formation, and evaluating toxicity.

Our findings indicate that oregano essential oil demonstrated strong antifungal activity, with MIC values below 3.125 mg/mL, making it one of the most effective choices amongst the oils tested. Additionally, in our antibiofilm studies, oregano significantly reduced biofilm formation, showing its potential for managing fungal infections.

In juxtaposition to other essential oils like lavender and thyme, which also exhibited notable antifungal properties, oregano stood out for its effectiveness. However, further research is necessary to fully understand the safety and efficacy of oregano oil as a topical treatment for candidiasis, which remains a widespread issue.

We believe these insights could benefit those seeking alternative treatments for yeast infections, with oregano essential oil being a promising candidate.
7
Oregano shows variable yeast effects
We explored the potential of oregano essential oil and its active ingredients, carvacrol and thymol, to combat various yeast infections caused by different strains of Candida. Our investigation included notable species like Candida albicans, as well as rising concerns, including C. glabrata, C. tropicalis, and C. krusei.

The study revealed significant variations in how each Candida strain reacted to these natural treatments, underscoring the fact that C. tropicalis showed more resistance compared to other strains. By utilizing techniques such as confocal laser scanning microscopy and scanning electron microscopy, we examined the structural changes in the cell walls and membranes of the yeast cells and observed how they responded biologically to the oregano treatments.

Notably, we also tested the effectiveness of oregano oil in living organisms, specifically in G. mellonella larvae. Our findings indicate a connection between the structure of yeast cell walls and their responses to oregano oil. Overall, while we found some promising information about the potential of oregano against yeast infections, there were still limitations to predictability based on the different strains involved.
We investigated the potential of oregano essential oil (OEO) encapsulated in keratin microparticles as an alternative treatment for vulvovaginal candidiasis (VVC), a common fungal infection among women. The main goal was to develop a method that would protect the essential oil and control its release, making it more effective against the fungal infection.

Our results showed that the oregano-loaded microparticles were stable over time and had a high encapsulation efficiency. We found that these microparticles not only penetrated well but also completely stopped the growth of the Candida yeast in a laboratory setting. Impressively, when we tested the microparticles in mice infected with Candida, a single application significantly reduced the yeast count while preserving beneficial bacteria.

This innovative approach using oregano essential oil microparticles presents a promising and natural alternative or complementary solution for treating yeast infections like VVC, while also maintaining the balance of healthy vaginal flora.
We set out to investigate how Origanum vulgare L. essential oil, commonly known as oregano oil, affects yeast infections caused by Candida species. Specifically, we aimed to determine whether this natural remedy could inhibit various virulence factors associated with these infections and enhance the effects of traditional antifungal medications like fluconazole and nystatin.

During our research, we analyzed both clinical strains of Candida albicans and several non-albicans strains. We employed various tests to measure oregano oil's influence on yeast growth, adherence to surfaces, and biofilm formation, which are all critical factors in the virulence of these fungi.

Our findings showed that oregano oil significantly reduced the growth and harmful behaviors of the Candida strains we tested. We identified minimum inhibitory concentrations indicating that small amounts of oregano oil could effectively inhibit yeast growth. Additionally, oregano oil demonstrated a synergistic effect when combined with fluconazole and nystatin, meaning it helped these medications work even better against the yeast.

Overall, oregano oil could be a valuable addition to antifungal treatments, offering a promising approach to combatting recurring yeast infections. This research highlights its potential as a natural remedy that, when paired with conventional therapies, could enhance treatment outcomes.
7
Oregano's combined antifungal potential
We investigated the effectiveness of oregano essential oil (EO) when combined with chlorhexidine against yeast infections, specifically targeted at both free-swimming and biofilm-forming yeast cells. The study utilized a checkerboard test to assess how well these treatments work together.

Our findings revealed that when oregano EO was combined with chlorhexidine, especially in the case of free-floating yeast cells, there was a noticeable additive effect. In a few instances, we even observed a synergistic effect with thyme and rosemary essential oils as well.

However, we found that while the combination did enhance antifungal activity compared to using each agent alone, it is essential to note that the study did not definitively establish oregano's effectiveness in isolation. This means that while oregano shows promise as part of a broader treatment approach, more research is needed to understand its potential on its own.

Overall, the combination of chlorhexidine and essential oils like oregano offers a compelling avenue for more effective treatment strategies against yeast infections, especially given the growing concern of resistance to standard antifungals.

References

  1. Váczi P, Čonková E, Malinovská Z. Synergistic effect of essential oils and chlorhexidine against planktonic and biofilm-forming cells of . Vet Anim Sci. 2024;26:100397. doi:10.1016/j.vas.2024.100397
  2. Fernandes L, Barco-Tejada A, Blázquez E, Araújo D, Ribeiro A, et al. Development and Evaluation of Microencapsulated Oregano Essential Oil as an Alternative Treatment for Infections. ACS Appl Mater Interfaces. 2024;16:40628. doi:10.1021/acsami.4c07413
  3. Oliveira ACD, Gobato C, Pereira KN, Carvalho MV, Santos JV, et al. Application of essential oils as natural antimicrobials in lactic acid bacteria contaminating fermentation for the production of organic cachaça. Int J Food Microbiol. 2024;424:110742. doi:10.1016/j.ijfoodmicro.2024.110742
  4. Angiolella L, Rojas F, Mussin J, Giusiano G. Modulatory effect of Origanum vulgare essential oil and carvacrol on Malassezia spp. virulence factors. Med Mycol. 2023;61. doi:10.1093/mmy/myad026
  5. Karpiński TM, Ożarowski M, Seremak-Mrozikiewicz A, Wolski H. Anti- and Antibiofilm Activity of Selected Essential Oils. Front Biosci (Landmark Ed). 2023;28:28. doi:10.31083/j.fbl2802028
  6. Stringaro A, Colone M, Cecchetti S, Zeppetella E, Spadaro F, et al. "In vivo" and "in vitro" antimicrobial activity of Origanum vulgare essential oil and its two phenolic compounds on clinical isolates of Candida spp. Arch Microbiol. 2022;205:15. doi:10.1007/s00203-022-03355-1
  7. Benziane MY, Bendahou M, Benbelaïd F, Khadir A, Belhadef H, et al. Efficacy of endemic Algerian essential oils against single and mixed biofilms of Candida albicans and Candida glabrata. Arch Oral Biol. 2023;145:105584. doi:10.1016/j.archoralbio.2022.105584
  8. Fernandes L, Costa R, Henriques M, Rodrigues ME. Simulated vaginal fluid: Candida resistant strains' biofilm characterization and vapor phase of essential oil effect. J Mycol Med. 2023;33:101329. doi:10.1016/j.mycmed.2022.101329
  9. Cid-Chevecich C, Müller-Sepúlveda A, Jara JA, López-Muñoz R, Santander R, et al. Origanum vulgare L. essential oil inhibits virulence patterns of Candida spp. and potentiates the effects of fluconazole and nystatin in vitro. BMC Complement Med Ther. 2022;22:39. doi:10.1186/s12906-022-03518-z
  10. Vinciguerra V, Rojas F, Tedesco V, Giusiano G, Angiolella L. Chemical characterization and antifungal activity of , essential oils and carvacrol against . Nat Prod Res. 2019;33:3273. doi:10.1080/14786419.2018.1468325
  11. Scalas D, Mandras N, Roana J, Tardugno R, Cuffini AM, et al. Use of Pinus sylvestris L. (Pinaceae), Origanum vulgare L. (Lamiaceae), and Thymus vulgaris L. (Lamiaceae) essential oils and their main components to enhance itraconazole activity against azole susceptible/not-susceptible Cryptococcus neoformans strains. BMC Complement Altern Med. 2018;18:143. doi:10.1186/s12906-018-2219-4
  12. Pradebon Brondani L, Alves da Silva Neto T, Antonio Freitag R, Guerra Lund R. Evaluation of anti-enzyme properties of Origanum vulgare essential oil against oral Candida albicans. J Mycol Med. 2018;28:94. doi:10.1016/j.mycmed.2017.12.001
  13. Ksouri S, Djebir S, Bentorki AA, Gouri A, Hadef Y, et al. Antifungal activity of essential oils extract from Origanum floribundum Munby, Rosmarinus officinalis L. and Thymus ciliatus Desf. against Candida albicans isolated from bovine clinical mastitis. J Mycol Med. 2017;27:245. doi:10.1016/j.mycmed.2017.03.004
  14. Liakos IL, Holban AM, Carzino R, Lauciello S, Grumezescu AM. Electrospun Fiber Pads of Cellulose Acetate and Essential Oils with Antimicrobial Activity. Nanomaterials (Basel). 2017;7. doi:10.3390/nano7040084
  15. Karaman M, Bogavac M, Radovanović B, Sudji J, Tešanović K, et al. Origanum vulgare essential oil affects pathogens causing vaginal infections. J Appl Microbiol. 2017;122:1177. doi:10.1111/jam.13413
  16. Bona E, Cantamessa S, Pavan M, Novello G, Massa N, et al. Sensitivity of Candida albicans to essential oils: are they an alternative to antifungal agents?. J Appl Microbiol. 2016;121:1530. doi:10.1111/jam.13282
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